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Univ.-Prof. Dr. Gundula Schulze-Tanzil,
Leitung
> Hier geht es zu den Forschungsgebieten der Anatomie
Institut für Anatomie,
Klinikum Nürnberg Medical School
Paracelsus Medizinische Privatuniversität, Nürnberg
Tel: 0911 398 - 6770
E-Mail: gundula.schulze@pmu.ac.at
Fax: 0911 398-6774
Mitgliedschaften und Engagement
- Seit 2004: Anatomische Gesellschaft
- Seit 2011: Deutsche Gesellschaft Orthopädie und Unfallchirurgie - Sektion/Vereinigung für Grundlagenforschung
- Seit 2013: Deutsche Gesellschaft für Orthopädie und Unfallchirurgie (DGOU)
2016
- Ruschke K, Meier C, Ullah M, Krebs AC, Silberreis K, Kohl B, Knaus P, Jagielski M, Arens S, Schulze-Tanzil G. Bone morphogenetic protein 2/SMAD signalling in human ligamentocytes of degenerated and aged anterior cruciate ligaments Osteoarthritis Cartilage. 2016 May 18. pii: S1063-4584(16)30099-1. doi: 10.1016/j.joca.2016.05.014. [Epub ahead of print]
- Huang Z, Kohl B, Kokozidou M, Arens S, Schulze-Tanzil G. Establishment of a Cytocompatible Cell-Free Intervertebral Disc Matrix for Chondrogenesis with Human Bone Marrow-Derived Mesenchymal Stromal Cells. Cells Tissues Organs. 2016;201(5):354-65. doi: 10.1159/000444521. Epub 2016 May 5.
- Badendick J, Godkin O, Kohl B, Meier C, Jagielski M, Huang Z, Arens S, Schneider T, Schulze-Tanzil G. Macroscopical, Histological, and In Vitro Characterization of Nonosteoarthritic Versus Osteoarthritic Hip Joint Cartilage. Clin Med Insights Arthritis Musculoskelet Disord. 2016 May 3;9:65-74. doi: 10.4137/CMAMD.S29844. eCollection 2016.
- Hammer N, Huster D, Boldt A, Hädrich C, Koch H, Möbius R, Schulze-Tanzil G, Scheidt HA. A preliminary technical study on sodium dodecyl sulfate-induced changes of the nano-structural and macro-mechanical properties in human iliotibial tract specimens. J Mech Behav Biomed Mater. 2016 Aug;61:164-73. doi: 10.1016/j.jmbbm.2016.01.018. Epub 2016 Jan 26.
- Hoyer M, Meier C, Kohl B, Lohan A, Kokozidou M, Schulze-Tanzil G. Histological and biochemical characteristics of the rabbit anterior cruciate ligament in comparison to potential autografts. Histol Histopathol. 2016 Aug;31(8):867-77. doi: 10.14670/HH-11-723. Epub 2016 Jan 21.
- Dey P, Schneider T, Chiappisi L, Gradzielski M, Schulze-Tanzil G, Haag R. Mimicking of Chondrocyte Microenvironment Using In Situ Forming Dendritic Polyglycerol Sulfate-Based Synthetic Polyanionic Hydrogels. Macromol Biosci. 2016 Apr;16(4):580-90. doi: 10.1002/mabi.201500377. Epub 2016 Jan 11.
2015
- Huang Z, Nooeaid P, Kohl B, Roether JA, Schubert DW, Meier C, Boccaccini AR, Godkin O, Ertel W, Arens S, Schulze-Tanzil G. Chondrogenesis of human bone marrow mesenchymal stromal cells in highly porous alginate-foams supplemented with chondroitin sulfate. Mater Sci Eng C Mater Biol Appl 50, 160-72.
- Schneider T, Welker P, Licha K, Haag R, Schulze-Tanzil G. Influence of dendritic polyglycerol sulfates on knee osteoarthritis: an experimental study in the rat osteoarthritis model. BMC Musculoskelet Disord. 2015 Dec 15;16:387. doi: 10.1186/s12891-015-0844-3
- Schneider T, Welker P, Haag R, Dernedde J, Hug T, Licha K, Kohl B, Arens S, Ertel W, Schulze-Tanzil G Effects of dendritic polyglycerol sulfate on articular chondrocytes Inflamm Res. 2015 Nov;64(11):917-28. doi: 10.1007/s00011-015-0875-0. Epub 2015 Sep 9
- Hoyer M, Meier C, Breier A, Hahner J, Heinrich G, Drechsel N, Meyer M, Rentsch C, Garbe LA, Ertel W, Lohan A, Schulze-Tanzil G. In vitro characterization of self-assembled anterior cruciate ligament cell spheroids for ligament tissue engineering. Histochem Cell Biol. 143(3), 289-300.
- Stölzel K, Kohl B, Hoyer M, Meier C, Szczepek AJ, Olze H, Schulze- Tanzil G. Effect of nasal sprays on an in vitro survival and morphology of nasoseptal cartilage. European Archives of Oto- Rhino-Laryngology and Head & Neck 272(4), 877-87.
- Stölzel K, Schulze-Tanzil G, Olze H, Schwarz S, Feldmann EM, Rotter N. Immortalised human mensenchymal stem cells undergo chondrogenic differentiation in alginate and PGA/PLLA scaffolds Cell Tissue Bank. 2015 Mar;16(1):159-70. doi: 10.1007/s10561-014-9457-6. Epub 2014 May 16.
- Hahner J, Hoyer M, Hillig S, Schulze-Tanzil G, Meyer M, Schröpfer M, Lohan A, Garbe LA, Heinrich G, Breier A. Diffusion chamber system for testing of collagen-based cell migration barriers for separation of ligament enthesis zones in tissue-engineered ACL constructs. J Biomater Sci Polym Ed. 2015;26(16):1085-99. doi: 10.1080/09205063.2015.1076714. Epub 2015 Aug 24.
- Nooeaid P, Schulze-Tanzil G, Boccaccini AR. Stratified Scaffolds for Osteochondral Tissue Engineering. Methods Mol Biol. 2015;1340:191-200. doi: 10.1007/978-1-4939-2938-2_14.
2014
- Jagielski M, Wolf J, Marzahn U, Völker A, Lemke M, Meier C, Ertel W, Godkin O, Arens S, Schulze-Tanzil G. The influence of IL-10 and TNFα on chondrogenesis of human mesenchymal stromal cells in three-dimensional cultures. Int J Mol Sci 15(9), 15821-44.
- Hoyer M, Drechsel N, Meyer M, Meier C, Hinüber C, Breier A, Hahner J, Heinrich G, Rentsch C, Garbe LA, Ertel W, Schulze-Tanzil G*, Lohan A*. Embroidered polymer-collagen hybrid scaffold variants for ligament tissue engineering. Mater Sci Eng C Mater Biol Appl 1;43, 290-9.*shared
- Girke G, Kohl B, Busch C, John T, Godkin O, Ertel W, Schulze-Tanzil G. Tenocyte activation and regulation of complement factors in response to in vitro cell injury. Mol Immunol 60(1), 14-22.
- Mrosewski I, Jork N, Gorte K, Conrad C, Wiegand E, Kohl B, Ertel W, John T, Oberholzer A, Kaps C, Schulze-Tanzil G. Regulation of OA associated key mediators by TNFα and IL-10: Effects of IL-10 overexpression in human synovial fibroblasts and a synovial cell line. Cell Tissue Res 357(1), 207-23.
- FANTOM Consortium. A promoter level mammalian expression atlas. Nature 507(7493), 462-70.
- Schulze-Tanzil G, Lemke M, Meier C, Ertel W, Kohl B, Huang Z, Muschik M, Markart M, Hoyer M, Arens S. Characterization of human anulus fibrosus– and nucleus pulposus–derived cells during monolayer expansion and in hydrogel cultures. Bone Tissue Regeneration Insights, 5.
- Lohan A, Marzahn U, El Sayed K, Haisch A, Müller RD, Kohl B, Stölzel K, Ertel W, John T, Schulze-Tanzil G. Osteochondral cartilage defect repair using autologous orthotopic and heterotopic chondrocytes in the rabbit model. Ann Anat 196(5), 317-26.
- Gröger D, Kerschnitzki M, Weinhart M, Schneider T, Kohl B, Wagermaier W, Schulze-Tanzil G, Fratzl P, Haag R. Selectivity in Bone Targeting with Different Polyanionic Dendritic Dye Conjugates. Advanced Healthcare Materials 3(3), 375-85.
- Stich S, Schulze-Tanzil G, Ibold Y, Stoll C, Abbas A, Kohl B, John T, Sittinger M, Ringe J. Expansion and characterization of human hamstring tenocytes on microcarriers. Biotechnology Progress 30(1), 142-51.
2013
- Lohan A, Stoll C, Albrecht M, Denner A, Krüger K, Ertel W, John T, Schulze-Tanzil G. Human hamstring tenocytes survive when seeded into a decellularized porcine Achilles tendon ECM. Conn Tiss Res 54(4-5), 305-12.
- Lohan A, Marzahn U, El Sayed K, Bock C, Haisch A, Kohl B, Stoelzel K, John T, Ertel W, Schulze-Tanzil G. Heterotopic and orthotopic autologous chondrocyte implantation using a minipig chondral defect model. Ann Anat 195(5), 488-97.
- Müller C, Marzahn U, Kohl B, El Sayed K, Lohan A, Meier C, Ertel W, Schulze-Tanzil G. Hybrid pig versus Göttingen minipig derived cartilage and chondrocytes show pig line-dependent differences. Experimental Biology and Medicine. (Maywood). 238(11), 1210-22.
- Busch C, Girke G, Kohl B, Stoll C, Lemke M, Krasnici S, Ertel W, Silawal, John T, Schulze-Tanzil G. Complement gene expression is regulated by pro-inflammatory cytokines and the anaphylatoxin C3a in human tenocytes. Mol Immunol 53(4), 363-373.
- El-Sayed K, Marzahn U, John J, Hoyer M, Zreiqat H, Witthuhn A, Kohl B, Haisch A, Schulze-Tanzil G*. PGA associated heterotopic chondrocyte co-cultures – implications of nasoseptal and auricular chondrocytes in articular cartilage repair? J Tissue Engin Reg Med 7(1), 61-72.
- El Sayed K, Zreiqat H, Ertel W, Schulze-Tanzil G. Stimulated chondrogenesis via chondrocyte co-culturing. J Biochips Tissue Chips S2:003. Sonderband: “Tissue Engineering”
- König J, Kohl B, Kratz K, Jung F, Lendlein A, Ertel W, Schulze-Tanzil G. Effect of polystyrene and polyether imide cell culture inserts with different roughness on chondrocyte metabolic activity and gene expression profiles of aggrecan and collagen. Clin Hemorheol Microcirc 55(4), 523-33.
2012
- Schulze-Tanzil G, Kohl B, El Sayed K, Arens S, Ertel W, Stölzel K, John T. Anaphylatoxin receptors and complement regulatory proteins in human articular and non-articular chondrocytes: interrelation with cytokines. Cell Tissue Res 350(3), 465-75.
- Al-Sadi O, Schulze-Tanzil G*, Kohl B, Lohan A, Lemke M, Ertel W, John T. Tenocytes, pro-inflammatory cytokines and leukocytes: A relationship? Muscle Ligament Tendon Journal Vol I (3), 68-76.
- Schneider T, Kohl B, Sauter T, Kratz K, Lendlein A, Ertel W, Schulze-Tanzil G. Influence of fiber orientation in electrospun polymer scaffolds on viability, adhesion and differentiation of articular chondrocytes. Clin Hemorheol Microcirc 52(2), 325-36.
- Schulze-Tanzil G, Al-Sadi O, Ertel W, Lohan A. Decellularized tendon extracellular matrix - a valuable approach for tendon reconstruction? Cells 1(4), 1010-1028. Special Issue: “Tissue and Organ Regeneration”.
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